Tuesday, May 19, 2009

Find out About Malignant mesothelioma

Malignant mesothelioma is a rare form of cancer that affects the mesothelial cells of the serous membranes in the body. The most common form of mesothelioma, affecting the lining of the lung, is pleural mesothelioma. Two to three thousand new cases of malignant mesothelioma are diagnosed each year.

The mission of All About Malignant Mesothelioma is to provide a one-stop resource for comprehensive, up-to-date mesothelioma information. We cover the full scope of malignant mesothelioma issues including background, history, risk factors, diagnosis, and treatment. Please recommend the site to someone who may benefit from mesothelioma information. All About Malignant Mesothelioma also includes comprehensive information on filing a personal injury or wrongful death lawsuit to obtain mesothelioma compensation.

Introduction to Malignant Mesothelioma

Malignant mesothelioma affects the lining or membranes of certain large cavities in the body. These cavities, called the serous cavities, house certain major organs in the body including the heart, lungs, abdomen and others. The membranes that surround these cavities are called the serous membranes. They serve to protect these major organs from the friction and abrasion that occur as the organs move against each other during typical daily functioning, such as breathing and heart beating. The serous membranes derive from specialized cells called mesothelial cells. These cells form to create the mesothelium, which is the major tissue layer of the serous membranes. Cancer that occurs in the mesothelium tissue is called mesothelioma.

Malignant mesothelioma takes on three forms:

  • Peritoneal mesothelioma, in the peritoneum or membrane surrounding the abdomen. A rare form of peritoneal mesothelioma can also affect the male testicles, because the lining around the scrotum is an extension of the peritoneum.
  • Pericardial mesothelioma, in the perdicardium or lining surrounding the heart.
  • Pleural mesothelioma, which is the most common form of malignant mesothelioma and affects the lining of the lung cavity.

All mesotheliomas are now considered to be malignant, or cancerous. They start as a localized tumor and spread rapidly to include most of the surrounding tissues and organs. Originally, fibrous cists and other non-cancerous growths that appeared in the serous membranes were thought to be mesotheliomas and were termed "benign fibrous mesothelioma" and "multicystic mesothelioma." These conditions are now known not to originate in the mesothelial cells, but other cells within the serous membranes. These conditions are typically localized, non-cancerous and do not spread rapidly.

Etiology of Malignant Mesothelioma

Most cases of malignant mesothelioma are associated with a previous exposure to fibrous minerals, of which asbestos is the most important. There is now indisputable evidence of the role of these fibers in the development of this disease. This has been demonstrated in animal experiments and many other experiments. Not everyone who is exposed to asbestos fibers has developed malignant mesothelioma, suggesting that other factors may also be involved.

Although malignant mesothelioma is rare, it is a serious, deadly disease. It is often in the advanced stages when it is detected, so the outlook for the patients is not as good as it is for the cancers that are detected earlier. The average survival time after detection is 1 to 2 years. This survival time also depends on the type of mesothelioma.

Further Malignant Mesothelioma Information

Please continue reading the articles on this website for more mesothelioma information and asbestos information. In addition, we recommend the following malignant mesothelioma resources:

Mesothelioma Cancer Treatments

Is there any promising research or are there promising drugs for mesothelioma?

New approaches being studied

New approaches to treat malignant mesothelioma are currently being tested. They often combine traditional treatments or include something entirely new. They include

  • Promising drugs


    • L-NDDP (Platar): Intrapleural administration of this platinum product is designed to overcome the toxicity and drug resistance currently limiting the usefulness of platinum drugs like Cisplatin. NOTE: A recent trial produced remission in two patients.


    • Endostatin has been shown to work with angiostatin in destroying a tumors' ability to grow blood vessels without harming normal cells.


    • Lovastatin is a cholesterol drug shown in a recent study to potentially inhibit mesothelioma cancer cell growth.


    • Intrapleural interferon gamma is the direct administration of the anti-cancer drug interferon gamma.


  • Photodynamic therapy kills cancer cells using the energy of light.


  • Immunotherapy treats cancer by helping the immune system fight the disease.


  • Gene therapy treats cancer by correcting the genetic deficits that allow tumors to develop. A September 1999 study found that interferon interleukin prevented the growth of mesothelioma cells in mice.

Research is being conducted at various cancer centers all over the United States.

A recent study involving L-NDDP produced two cases of remission in mesothelioma patients. Another study found that a drug known as Lovastatin may hold promise for mesothelioma patients.

To learn more about mesothelioma clinical studies and journal medical journal articles, visit the Mesothelioma Web (http://www.mesotheliomaweb.org)

What other kinds of information is available for people with mesothelioma?

There are numerous cancer web sites, some specific to mesothelioma. Because they are often difficult to locate, we have listed some relevant medical web sites that have information about mesothelioma.

(http://www.aicr.org)

(http://www.thoracic.org/)

(http://www.bc.cancer.ca)

(http://www.mesotheliomaweb.org)

Mesothelioma At A Glance
  • Mesothelioma is a cancer that arises from the cells lining the chest or abdominal cavities.
  • Mesothelioma typically results from exposure to asbestos.
  • When mesothelioma affects the chest, the doctor may look inside the chest cavity with a special instrument called a thoracoscope.
  • When mesothelioma affects the abdomen, the doctor may look inside the abdomen with a special tool called a peritoneoscope.
  • Mesothelioma is diagnosed by a biopsy.
  • The outlook for patients with mesothelioma depends on how early the disease is detected and how aggressively it is treated.

Tuesday, April 7, 2009

Effects of Mesothelioma Cancer

Most organs in the body and is protected by a layer of cells or specific membrane Mesothel. The Mesothel contains two layers of cells: an immediate surroundings, and the other a thick layer to the previous one. This membrane is a secret liquid lubricant between the two layers, so that the institutions themselves without any problems and against neighbors (such as the expansion and contraction of the lungs, the heart of the so ..)

Depending on the situation in the body, Mesothel different names. Mésothéliales substance, most of the organs in the abdominal peritoneum. The membrane surrounding the lungs and chest wall of the pleural cavity. The heart and through the tissue called pericardium.

Mesothelioma, cancer of the Mesothel is a disease in which abnormal cells divide and Mesothel much, and without order, the development of tumors. Tumor cells mésothéliales may be benign (not cancerous cells) or malignant (cancer). Since most tumors are cancerous cells mésothéliales, malignant mesothelioma is often referred to simply as mesothelioma. You can damage tissues and organs as well. The metastatic cancer cells can also hand of parents in other parts of the body.

Malignant mesothelioma affect the mucous membranes or a few large body cavities. These caves, grottos Leimohr called by some organs of the body including the heart, lung, stomach and others.

Malignant mesothelioma in three ways:
• peritoneal mesothelioma in the peritoneum or membrane surrounding the abdomen.
• Pericardial mesothelioma: pericardium, or the lining that surrounds the nucleus.
• pleural mesothelioma is the form of malignant mesothelioma and affects the lining of the lung cavity.

Most cases of malignant mesothelioma with an exhibition against the mineral fiber structure, which asbestos is the most important. Asbestos is a mineral that is naturally stronger, more flexible fibers can be separated in the spinning and weaving fine. Asbestos has been used in many industrial products including cement, brake linings, roof tiles, coatings, textiles, and insulation. Especially during the production, which is inhaled or ingested with ease in the manufacture of asbestos dust and small particles that are floating in the air.

The period between exposure and the development of mesothelioma is typically 35-40 years. In general, people who developed mesothelioma asbestos over a longer period, but with some people who have a short exposures mesothelioma. Moreover, not all workers who are highly vulnerable to developing mesothelioma.

Before the 1970s, large quantities of asbestos in the construction and shipbuilding. After the public health risks of asbestos is known for the production of asbestos has been drastically in the 1970s. The state has restrictions on its use and other materials are available. Despite these changes, asbestos is still used.

The professions which deal with asbestos and usually with the onset of mesothelioma later in life with the manufacture of asbestos insulation, heating capacities of shipyards and construction.

Mesothelioma Cancer - Causes and Symptoms

Mesothelioma is a cancer of the lining Mesothel or membrane that protects and most organs in the abdominal cavity. The first layer of the body and the second layer is a pocket of protection. It is a lubricating fluid between the layers to the movement. Mesothel pericardium is recognized when it is the heart, the pleura, the lung and peritoneum, in the abdomen.

In mesothelioma, it is not controlled by the cell responsible for the extra-cellular invasion of proximity to the masses of tissue and organs and cause damage. Above all, it should be noted that mesothelioma begin in the pleura and peritoneum. Cancer and metastases in other parts of the body.

Mesothelioma is mainly due to exposure to asbestos. This is considered an important risk factor. 70% to 80% of patients in the history of exposure to asbestos. There are exceptions for cases were asbestos exposure has been the absence. The situation is more common in men than in women. It was also found that the risk increases with age.

Mesothelioma is a rare disease. Above all, it is said in the context of exposure to asbestos. Asbestos is a mineral collection, as large masses of films or fibers flexible. It is widely used in industrial products like cement, roofing, coatings, textiles, brake linings and insulation. Small particles of asbestos in the air and can be inhaled or swallowed by people who, like workers in the manufacturing companies, etc.

An exhibition for a period can cause asbestosis. Exposure to asbestos increases the risk of mesothelioma and other cancers, such as kidney and larynx. There are limits on exposure to asbestos was in force, in working with minerals. Another interesting aspect is that mesothelioma family members of people who are exposed to asbestos at work show an increased incidence of breast cancer compared with others. Has been assigned to the remains of asbestos particles, according to the clothing, hair, etc at home, the family members.

Cancer is about thirty to forty years, to the surface. The first symptoms are shortness of breath and chest pain, if they change the color of the pleura are affected. If peritoneal cancer is weight loss, swelling and pain in the abdomen, the accumulation of fluid in the abdomen, intestinal obstruction. Fever, anemia and bleeding were also noted irregularities. In severe cases, there is a swelling of the face and neck, difficulty swallowing and pain.

The diagnosis of mesothelioma is very difficult because there are no symptoms. A review of medical history would be very useful, and that exposure to asbestos. X-ray of the chest, abdomen, lung function tests, MRI of the usual tools to help confirm the diagnosis. Biopsy for confirmation and therapy and radiation.

Saturday, April 4, 2009

New Mesothelioma Treatment

Individuals diagnosed with mesothelioma are often confronted with a confusing array of possible treatment options. Traditional forms of treatment include chemotherapy, radiation, and surgery. However, a number of experimental and alternative treatments are now being investigated by physicians around the world. In some cases, these new treatments are already helping to extend the lives of patients.

Gene therapy is used in conjunction with chemotherapy, in order to increase the possibility of its success. This type of therapy is commonly called suicide gene therapy, because it causes cancer cells to turn against themselves. Other types of gene therapies use alternate methods to reduce cell growth and prevent the cancer from spreading.

Another type of new treatment approach is known as photodynamic therapy (PDT). It is another method of destroying cancer cells by exposing them to a special laser light. The light activates photosensitive medication within the cells, which is taken by the patient prior to exposure. The cells are destroyed once the light reaches them. Unfortunately, this type of treatment is not always effective. In addition, there are several potential side effects, including skin sensitivity and nausea.

There are also several experimental drugs being used to treat mesothelioma. A category of drug known as anti-angiogenesis medications attempt to destroy cancer cells while leaving other cells unharmed. This is possible due to new knowledge about the manner in which cancer cells differ from normal cells. Using these drugs, the need for chemotherapy is reduced.

A final type of experimental treatment is immunotherapy. This method uses the patient's own immune system to kill cancer cells. Normally, our immune systems are unable to distinguish between healthy cells and cancerous cells.

Immunotherapy attempts to enhance a patient's immune system to differentiate between the two, allowing it to fight back against the cancer cells. This is usually accomplished via a vaccine or oral medication. However, this form of treatment is quite new and doctors are still working to determine its viability.

Mesothelioma Cancer

Malignant mesotheliomais a relatively uncommon form of cancer that is caused by exposure to asbestos, usually in the workplace. It affects the mesothelial cells that line three of the body's largest cavities surrounding the lungs, heart and abdomen and is an aggressive form of cancer. Pleural mesotheliomais the most common form of mesothelioma, accounting for approximately 75% of all mesothelioma cases.

Found between the lungs and the chest cavity, the pleura is a thin membrane that provides a lubricated surface so that the lungs can manouver easily against the chest walls while breathing. The pleura also serves as a protective layer. Pleural mesothelioma is often incorrectly described as a form of lung cancer due to the pleura's close proximity to the lungs.

The second most common type of mesothelioma is peritoneal mesothelioma. This form accounts for approximately between 10-20% of all mesothelioma cases, or mesothelioma of the peritoneum. The peritoneum is a thin serous membrane that encapsulates the organs of the abdomen.

While peritoneal mesothelioma is not as common as pleural mesothelioma, it tends to be much more invasive and aggressive, typically yielding a shorter life expectancy for diagnosed patients. Pericardial mesothelioma is a lesser known form of the disease, accounting for less than 10% of all mesothelioma cases, or mesothelioma of the pericardium. The pericardium is the membrane that protects your heart, also referred to as the heart sac. The rarest form of mesothelioma is called tunica vaginalis testis and can originate in the lining surrounding the testicles.

Asbestos exposure is the only known cause of mesothelioma. Typically the result of occupational duties, mesothelioma can result from brief exposure to asbestos fibers. It has been determined that the dangers associated with working with asbestos have been known for over seventy years; however, employers chose to keep this knowledge disclosed for fear that it could have a negative impact on profitability. Even in this day and age, employees are often not properly notified that asbestos could be present in their working surroundings. This can result in any number of asbestos related diseases including the most serious, malignant mesothelioma.

Mesothelioma pain medications

Almost everyone with mesothelioma experiences pain, the more so as the disease advances. Most patients use of a variety of pain medications to reduce pain and maintain their quality of life. Here are the kinds of pain that people with mesothelioma must deal with, and the types of pain medications used to control the pain.

Mild to moderate pain

Non-opioids: Examples are acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen. You can buy many of these over the counter, without a prescription. Some stronger NSAIDs do require a prescription.

Tingling and burning pain

Two other groups of drugs, antidepressants and antiseizure medications, have proven to be very useful in managing tingling and burning sensations. Taking an antidepressant does not mean that you are depressed or have a mental illness, and taking an antiseizure medication does not mean that you are going to have seizures. If your doctor prescribes one of these s/he is simply making use of some additional therapeutic properties of these drugs.

Antidepressants: Drugs such amitriptyline, imipramine, doxepin and trazodone have proved helpful in alleviating pain when there has been nerve damage. They are also helpful as aids for sleeping. A prescription is needed for these medicines.

Antiepileptics: Carbamezeping, lamotrine, and gabapentin are three of the most used antiseizure medications. All of these require a prescription.

Moderate to severe pain

Opioids: Examples are hydrocodone, codeine, morphine, hydromorphone, oxycodone, fentanyl and methadone. All of these medications require a prescription. Nonopioids may also be used along with opioids to control moderate to severe pain.

Breakthrough Pain

ACTIQ (Oral Transmucosal Fentanyl Citrate) is the first analgesic (pain relief) drug approved by the Food and Drug Administration specifically for breakthrough pain. It comes as a lozenge on a handle, a lollipop for pain. Fentanyl, ACTIQ's active ingredient, is a very effective opiate, 100 times stronger than an equivalent dose of morphine. It dissolves in saliva, and is absorbed through the mucus membranes that line the mouth. Pain relief occurs within 5 to 10 minutes. People find the drug easy to use, effective, and easily tolerated. Oxycodone and hydromorphone can also be used for breakthrough pain, but neither of these are available as lozenges in the mouth absorption.

Mesothelioma chemotherapy

Active control of the symptoms of mesothelioma in chemotherapy studied

According to a recent issue of the British medical journal, The Lancet, researchers have been studying the effect of chemotherapy in mesothelioma. Because chemotherapy is not considered a successful treatment for mesothelioma cancer, but a treatment for mesothelioma signs and symptoms of medical professionals to continue the discussion of the usefulness of the procedure in controlling symptoms.

The researchers studied 409 patients of all who suffer from malignant pleural mesothelioma in different parts of the world. Patients were randomly assigned a treatment of symptoms or treatment that included an active control treatment with two chemotherapy drugs. According to the study, "the active symptom control treatments include steroids, bronchodilators, analgesic drugs and palliative radiotherapy."

After the study, patients in both treatment options were compared and, according to investigators, "the addition of chemotherapy to control the symptoms showed a non significant benefit or advances in survival or quality of life" among the victims of mesothelioma.

What is mesothelioma, chemotherapy?

Mesothelioma is a malignant disease in which cancer cells develop in a thin layer of tissue that is the thoracic cavity that covers the lungs, which is also known as the pleura or peritoneum, the tissue lining the abdomen and Most of the bodies, according to the National Cancer Institute (NCI).

According to the American Cancer Society (ACS), chemotherapy is a treatment method that uses chemicals commonly administered through a catheter, pill, injection, or the port, which is usually a round disk of metal or plastic , which is when cancer cells begin to develop abnormal and divide uncontrollably fast. Chemotherapy is given for a variety of reasons, but is based on certain factors such as stage of cancer, a patient's health and age of a patient. For patients with mesothelioma, chemotherapy is not a method of cure, but is administered to patients with mesothelioma for several reasons including:

* Halting the growth and spread of cancer, to control cancer
* Minimize or reduce tumors - this method is also known as neoadjuvant chemotherapy
* The palliative chemotherapy on pain and other symptoms have to be reduced
* The destruction of microscopic disease that remains after a surgical procedure, also known as adjuvant chemotherapy

Chemotherapy is given as a catheter into a large vein in the body or a catheter is attached as a port that is placed on the chest under the skin for a period of time.

Living with Mesothelioma

Unfortunately, victims of mesothelioma receive further setbacks in his life-threatening condition, as currently there is no successful treatment for cancer death. However, a person has the opportunity to participate in a series of clinical trials of the treatment groups, as well as the opportunity to develop mesothelioma a demand for monetary compensation as a means of payment for the condition, which is often associated with the very expensive medical bills.

Lung Cancer

It is very rare for lung cancer to only have one cause; we know that because not everybody who smokes cigarettes gets lung cancer. I had an uncle who smoked most of his life and died at the grand age of 99. Fortunately he was smart enough to give up smoking in his sixties. Rather than simply being caused by passing smoke through your lungs, lung cancer is typically triggered by many causes, smoking being the main one. The other causes of lung cancer are nutritional deficiencies, toxins in your environment, our sedentary lifestyle and sometimes emotional conflict.

Now passing smoke through your lungs is not a very clever thing to do, we do it at a young age because we think we're invincible and maybe we are, but as we age we most definitely are not. The biggest health problem with the habit of smoking is, it inhibits the body from absorbing the vitamins and minerals we so badly need to maintain our health. It also irritates the delicate linings of the lungs and cancer will take hold in some part of the body that has been weakened by any damage or irritation.

The food we eat on a daily basis is the foundation of our health. Our diets today have changed vastly and the typical western diet is not known for its health giving qualities. We may think we are eating well but when you consider that we are designed to eat only freshly grown fruit and vegetables, a few whole grains and one or two other items one can see that we have strayed far from a healthy diet. A big percentage of our food intake these days is processed food and nearly all of it is nutritional dead food because of its processing and because it's old. Our poor food choices are most certainly a major contributor to all cancers.

Most of the chemicals we surround ourselves with these days are extracted from crude oil, in other words the petro-chemical industry and they do effect us. 100 years ago there weren't any chemicals but today we are overwhelmed by them. We breathe them in as in exhaust gases from motor vehicles, we use them on our body as in personal care products, even so called natural ones have some chemicals in them, and we take them in directly in the form of food additives. They are also in the homes we live in, because of the many products used in the building industry.

The human body was designed to be physically active and if we neglect this basic function we'll inevitably pay the price in the form of health problems. Some form of exercise on a daily bases is very important to both avoid cancer and to fight cancer. Once again because of the motor car and cheap oil, we seldom get the exercise we so badly need. When we exercise we are enriching our bodies with oxygen and cancer cells cannot survive in an oxygenated environment. That was proven back in 1931.

Emotional conflict can weaken our immune system and that is well recognised. It's because we're holding onto a problem like a personal crises in some form and it's wearing us down. The only solution I can suggest is to seek help to resolve the issues.

Our bodies have amazing self healing powers that can eliminate cancer, but we have to provide the right conditions to allow that to happen. The bottom line is, you need to take charge of your cancer and no one can do it for you. Appropriate diet and lifestyle changes are your first line of defence.

Malignant mesothelioma

Malignant mesothelioma is a type of cancer that is quite rare; it affects only the thin wall of cells that line the internal organs and structures. This lining is called the mesothelium and malignant mesothelioma can manifest itself in three main ways. It can be pleural which affects the lungs, peritoneal which affects the abdominal cavity wall and pericardial which affects the lining in the heart. Experts believe that there is only one way to contract malignant mesothelioma and that is through exposure to asbestos.

Asbestos is a naturally occurring mineral that is highly toxic to humans yet was once used in abundance in the building and construction trades. It was used as it has a very high tolerance of heat and it is remarkably strong, it was also very cheap. It is made of fibres which are microscopic and can be airborne when ceilings covered with asbestos crack or when it is otherwise exposed to the air. When fibres of asbestos get inside the body they cannot be broken down or expelled and this will result in serious scarring of the mesothelioma and inflammation. Once this scarring occurs it is only a matter of time before malignant mesothelioma takes hold in one of its various forms.
Symptoms of malignant mesothelioma can initially be quite hard to spot as they can be quite unnoticeable.

As a result they can be passed off as being day to day illnesses and this can cause even more problems as this delay gives malignant mesothelioma even more time to take hold of a person. It has been known for people with malignant mesothelioma to live with their symptoms for up to six months before they seek medical help with them. Symptoms of the various forms of malignant mesothelioma can include - shortness of breath, weight loss, nausea, vomiting, persistent coughing with or without blood in it, abdominal pains, stomach pains, chest pains, pain in the lower back and in some cases swelling of the face and arms and a loss of sensory capabilities. As these symptoms are so wide ranging and often seemingly unconnected it is no wonder that it can be difficult to obtain a correct diagnosis. Experts now recommend that anyone who has had prior exposure to asbestos at some point in their lives gets checked out for malignant mesothelioma even if they feel fit and well. Doing this could vastly extend a person's life who could go on to be diagnosed with malignant mesothelioma.

Treatment for malignant mesothelioma can vary and surgery should only be an option if the disease is diagnosed in the very early stages. Otherwise it is more common for a person to undergo chemotherapy or radiotherapy to attempt to control the malignant mesothelioma. Although there is no known cure for malignant mesothelioma it can be controlled for some time if it is caught in time. Otherwise the outlook is not particularly positive and the best that many people with malignant mesothelioma can hope for is to be able to manage their symptoms and pain with painkillers and other medication.

Mesothelioma Info

Mesothelioma is a rare form of cancer, usually caused by exposure to asbestos. When an individual is diagnosed with the disease, there are many questions which will invariably go through their mind. Perhaps the most important one involves the patient's prognosis. That is, what is the life expectancy for someone diagnosed with mesothelioma?

As with any form of cancer, the survival rate for this condition is heavily dependent on how early it is diagnosed. If the disease is already in an advanced state when it is first detected, it will require far more aggressive treatment, with a reduced chance of success.

Unfortunately, the survival rate for mesothelioma has historically been rather low. Many patients do not survive longer than one year after diagnosis. The disease has often spread significantly before it is diagnosed, making it that much more difficult to treat. This is due to the fact that an individual exposed to asbestos can live for decades before any noticeable symptoms present themselves.

In addition, patients diagnosed with mesothelioma are often 55 years of age or older, and may have other medical conditions which complicate their treatment.

The good news is that there are many long-term survivors of mesothelioma, some of whom have lived a decade or more following diagnosis. Some doctors believe these patients survive longer not because of their particular treatment method, but because of other health characteristics specific to the individual. In general, healthier patients with no other existing medical conditions are more likely to survive longer than those with additional diseases and afflictions.

In terms of raw numbers, statistics show that about 10 percent of individuals with mesothelioma live for at least five years after being diagnosed. About 40 percent of those diagnosed survive for at least one year. These numbers are significantly higher than they were just 20 years ago, giving hope to doctors and patients alike.

A few of the other factors that affect survival rates include the specific type of mesothelioma with which an individual is diagnosed, the size and location of their tumor, and whether or not the patient is a smoker. These factors are in addition to the patient's age, any existing medical conditions they may have, and severity of the cancer itself.

Pleural Mesothelioma: Warning Signs

If you have ever been exposed to asbestos, whether directly or from a spouse whom was, then you will want to read this article. There are two main symptoms of pleural mesothelioma that you need to look out for: difficulty breathing and chest pain. I will explain each in this article so that you have a better awareness of when you need to put the pride away and go see a doctor.

Mesothelioma is a type of cancer found in the lungs and abdomen. Estimates show it affects over 2000 people every year in the states alone. This disease is the direct result of asbestos exposure. However, nearly a quarter of all diagnosed had no exposure to asbestos. So even if you never had exposure and you find yourself with the following pleural mesothelioma symptoms you need to see a doctor.

Pleural mesothelioma is cancer that is found in the pleura of the lungs. The pleura is the lining or membrane that surrounds the lung tissue. This lining has two layers: visceral and parietal. The visceral is the inner layer while the parietal is the outer. In between them is lubricating fluid to help the two layers slide over each other as our lungs contract and expand for our breathing. When one begins the early stages of pleural mesothelioma the cancer can cause the layers to become thicker. This can result in the pleural mesothelioma symptoms; difficulty breathing and chest pain.

Obviously difficulty breathing is a common symptom for many ailments. So don't conclude that you have mesothelioma. You need to visit a doctor as soon as you can.

In pleural mesothelioma you begin to have shortness of breath and difficulty breathing because of the two layers of the lining pushing against each other. The layers create more tension because they become thicker as mesothelioma develops. This can also cause discomfort from swallowing and regular coughing. It can also cause hoarseness of the throat and coughing up of blood.

Another symptom is pain in the chest. Naturally as the layers become thicker due to the growth of cancer cells and push against your lungs causing shortness of breath they can also cause chest pain because of the added pressure. The pain typically begins on the side and spreads up to your shoulders and neck.

If you experience either of these symptoms you should consult a doctor right away. As pleural mesothelioma spreads the symptoms will become worse. Visit a doctor and make it a point to notify him or her if you have had any exposure to asbestos and your history of it. There is evidence that a person can get this cancer indirectly from exposure to someone that had direct exposure with asbestos. So if your spouse worked in a high asbestos exposure occupation make sure you tell your doctor.

Mesothelioma Documentation

It is documented that Australia had the highest per capita use of asbestos in the world from the 1950’s until the 1970’s. As a tragic consequence, Australia now has the highest per capita incidence of mesothelioma in the world. With more than 500 Australians contracting mesothelioma per year, it is estimated that up to 18,000 Australians will die from this asbestos related cancer by the year 2020.

Despite the growing awareness of the dangers of asbestos, there are many people who have not heard of Mesothelioma. This asbestos related cancer is defined as: a malignant spreading tumor of the mesothelium of the pleura, pericardium, or peritoneum, arising form the inhalation of asbestos fibers.

One of the most baffling and frightening known facts concerning Mesothelioma is that many years may pass, between inhalation of asbestos dust and its deadly legacy of disease; it is not uncommon for four decades or more to pass before symptoms due to asbestos dust inhalation become apparent.

In November 2004, I was an invited speaker at the Global Asbestos Congress 2004, held in Tokyo Japan. Over 800 participants from 40 countries around the world were in attendance. To be a part of such a large gathering of fellow humans, united in a quest to rid the poison of asbestos from our environments was an intensely moving experience. Having lost my husband to mesothelioma I know first hand the suffering this cruel disease places on its innocent victims.

There were many speakers and each told a tale, of pain, death and heartache. We listened, we understood and we ached for the past, present and future victims of the killer asbestos and its legacy of mesothelioma and other asbestos related diseases. We listened and we were shocked and angered to learn that despite the growing awareness of the dangers of asbestos and the increasing incidence of asbestos related disease, there remains some countries who are mining asbestos with little or no regard for their workers or people who will come into contact with asbestos products.

Asbestos disease Association member’s world wide are working tirelessly and fighting almost insurmountable odds to ban asbestos from all countries of the world. It is a sobering and frightening fact, that even if we were successful today in this quest, the legacy of asbestos related diseases will continue for five decades.

Add your voice to the many who want this killer product erased from the worlds environments – Add your voice to the call that pleads for adequate compensation for victims and their families. Sign the online petition at Asbestos Disease Awareness Organization:

The Asbestos Disease Awareness Organization (ADAO) continues to raise public awareness about the dangers of asbestos exposure and the incurable and often deadly asbestos related diseases. ADAO is quickly expanding and uniting veterans, fire-fighters, shipbuilders, teachers and thousands of other innocent people around the world. Asbestos Awareness leads to education, prevention, new treatments and ultimately a cure.
http://www.asbestosdiseaseawareness.org

Friday, March 27, 2009

MesotheliomaTreatment Stages

The treatment protocol for mesothelioma differs based on the stage that a patient has progressed to at the time of diagnosis. Provided below is an example of the types of treatment that a pleural mesothelioma patient will undergo at various stages of the disease. We have identified the stages using the Butchart staging system.

Stage I Mesothelioma Treatment

Surgical intervention is most commonly recommended for pleural mesothelioma patients having a Stage I diagnosis. The procedures that are likely to be performed are pleurectomy/decortication or extrapleural pneumonectomy. Post surgery, doctors may further evaluate the patient to determine if chemotherapy or radiation treatment is necessary. It is often determined with stage I mesothelioma that those adjunct therapies are not required.

Stages II, III Mesothelioma Treatment

When mesothelioma has progressed to stages II and III the cancer cannot be cured. At these stages medical treatment focuses on alleviating the severity of the symptoms and keeping the patient as comfortable as possible in order to optimize quality of life. For example, if there is significant fluid build-up in the chest the doctor may order that it be drained. Additionally, there may be instances where removing some or all of the tumor and / or undergoing chemo or radiation treatments will provide symptom relief. clinical trials at some of the larger cancer centers in the country may also offer different treatment options for patients in these stages.

Stage IV Mesothelioma Treatment

When a patient has been diagnosed with stage IV mesothelioma the prognosis is very unfavorable. At this stage, the cancer has usually metastasized throughout the body to other organs and as with stages II and III, cannot be cured. In this stage, symptoms generally increase in severity and pain management becomes the primary focus of the medical team. Therapies such as chemotherapy and radiation are typically not offered at this stage unless they are needed to support pain management objectives. Oftentimes families find that it is most helpful to seek out additional support through a local Hospice program. Hospice programs focus on providing patient care, developing a pain management protocol and providing support for both the patient and family members at this difficult time. Patients with stage IV mesothelioma may also be interested in participating in specialized clinical trials offered at leading cancer hospitals and centers and are encouraged to seek out those programs if desired.

Mesothelioma and Smoking

Smoking tobacco products has long been held as the world's culprit for any disease. Fortunately for smoking, it is not the culprit behind mesothelioma. In fact, smoking does not ever cause mesothelioma. So far, the only scientifically linked cause of mesothelioma has been exposure to asbestos.

While it is true that smoking does not cause mesothelioma, it does not help anyone who has been diagnosed either. In addition, those who have been exposed to asbestos, either recently or a long time ago, should not smoke because smoking increases the chances of developing mesothelioma due to asbestos exposure.

Once a person has been exposed to asbestos, smoking is known to complicate the chances of developing an illness directly linked to asbestos. People who smoke and have been exposed to asbestos have 50 to 84 times the chance of developing asbestos as people who do not smoke and have been exposed to asbestos. There is therefore a related effect between smoking and asbestos, although smoking does not cause mesothelioma.

In the case of people who are scared that they will develop mesothelioma after being exposed to asbestos, the best thing to do is quit smoking. Smoking is known to weaken and damage the lungs. In addition, it is known to reduce the body's natural defenses and ability to remove asbestos fibers. When the fibers cannot be removed by the body, they are allowed to stay in the lungs and continue to irritate cells. This leads to more cell damage and scarring which increases the odds of developing mesothelioma down the line.

Another nasty side effect of smoking is that smoke from cigarettes irritates air passages and causes the body to produce more mucus in the lungs. The production of mucus prevents air from getting into the deeper parts of the lungs and in turn prevents the removal of asbestos fibers.

Once a person knows he or she has been exposed to asbestos, the top priority should be working on quitting smoking. A smoker that has ever in their entire life been exposed to asbestos should see a doctor to be checked for symptoms of mesothelioma and other diseases that are directly related to asbestos. Even if there aren't any signs or symptoms of the disease, the trip to the doctor is imperative for early detection.

Asbestos and Mesothelioma

How asbestos fibers enter the lungs

Asbestos is a term for a group of magnesium silicates that have fibrous structure. Asbestos minerals consist of fibers that are easily separable. Individual fibers are extremely small and fine, light enough to be carried in the air. Doctors who treat lung disease consider all forms of asbestos dangerous, and capable of causing cancer. The six most common are amosite, chrysotile, crocidolite, and the fibrous varieties of tremolite, actinolite, and anthophyllite. Amphibole forms of asbestos, whose fibers are straight, are more likely to cause disease than chrysotile, whose fibers are curved.

In the course of mining, manufacturing and installing products using asbestos, tiny fibers are dislodged and become airborne. Workers in an environment where asbestos is used cannot avoid inhaling the airborne fibers. Poor ventilation and insufficient or no protective apparatus increase exposure to this lethal fiber. Workers have described mining and factory environments where the air was white with asbestos dust, and their clothes and hair were covered within the fine white fibers.

How asbestos fibers damage the lungs

Most fibers are cleared from the lungs within hours of inhalation. Coughing carries them to the throat in a layer of mucus, where they are either spit out, or swallowed, and make their way out of the body.

Not all inhaled asbestos is cleared from the lungs. Some fibers progress into the alveoli, the tiny pockets within the lungs where oxygen is exchanged with the bloodstream. The fibers may remain for years, even the rest of a person's life. Amphibole asbestos fibers, which are longer and straighter than chrysotile fibers, tend to remain in the lung the longest.

Asbestos fibers move toward the lower portion of the lungs and the diaphragm, the large muscle that moves the lungs in breathing, which sits just under the lungs. In autopsies, most asbestos disease of the lungs is seen the bottom lobes of the lungs and on the surface of the diaphragm. Asbestos fibers which lodge in lung tissue and are not expelled continue to damage the tissue as long as they stay there, as the mesothelioma grows slowly and silently. Symptoms may not appear for 15 to 40 years after exposure.

Asbestos fibers and mesothelioma

Asbestos fibers work their way through the lungs into the pleural cavity, the space in the chest where the lungs sit. The asbestos fibers invade the mesothelium, the thin, moist, flexible tissue that lines the cavity. Mesothelioma specialists have two theories about how asbestos in the pleural cavity causes mesothelioma. One theory is that as the asbestos fibers migrate through the pleural cavity, they enter tissue walls and irritate tissues. The irritated cells respond by forming scar tissue. The mesothelial cells show an inflammatory immune response, scarring, and eventually the uncontrolled proliferation of cells that is the hallmark of cancer.

The second theory focuses on events at a molecular level, speculating that asbestos fibers interact with individual mesothelial cells, interfering with their cell division, or possibly damaging the cell's DNA during mitosis, or cell division. The part of the DNA that regulates the cells' growth and reproduction is damaged, so that reproduction is no longer controlled. Cells begin to reproduce wildly. This uncontrolled cell growth creates the thickened cancerous tissue and eventually begins to invade other organs.

Although the highest risk of developing mesothelioma comes from prolonged exposure to asbestos fiber, some people who develop mesothelioma have had only very brief exposure. The first symptoms of mesothelioma may not show up for 15, sometimes for as long as 30 or 40 years after the victim's exposure to asbestos. By the time symptoms are painful enough for a victim to seek medical attention, the disease may have progressed so far that life expectancy will be measured in months.

If you or a loved one has received a diagnosis of mesothelioma, and you believe that the mesothelioma developed as a result of workplace exposure to asbestos, you may have a legal claim against the corporation that permitted the exposure, or the manufacturer of the asbestos product. To learn more about your rights, you should consult a lawyer who specializes in asbestos claims.

Mesothelioma Attorney

  • A person who has encountered a mesothelioma lung cancer or other related disease is in a very critical position both in terms of health and finance. It should file lawsuit against the company responsible for his suffering and claim a compensation amount in order to deal with his precarious condition.

  • It is when an Attorney comes into picture. Being a legal expert he is in a position to deal the case and take every effort to ensure a reasonable compensation claim for his client.

  • For all that a lawyer does processing a lawsuit in favor of his client; he charges a hefty sum as fees towards his professional services.

  • The normal practice is that the victim is not required to pay the Mesothelioma legal expert any fees unless the legal firm gets a reasonable financial settlement for you.

  • The fee quoted by an attorney is normally charged on a contingency basis depending upon the success of the case and reasonable financial compensation received from the company.

  • Amount handed over to the client will be the net amount. It is important to note that irrespective of the fee charged by the attorney, the net amount after the settling the fee amount should be sufficient for the victim and his family.

  • While preparing for the case a Mesothelioma attorney incurs a number of expenses ranging from travel, research, hiring experts and getting depositions. Hence attorney's fees include a percentage on the amount of compensation received together with reimbursement of expenses incurred on behalf of the client.

  • It is important to understand the cases involving huge compensations and corporate interest generally takes number of years of trial. Hence the professional charges will be accordingly high.
  • Asbestos Cancer

    Exposure to a constant and high level of asbestos can often times lead to cancer. Mesothelioma and lunch cancer are to of the most common asbestos cancers reported today. Gastrointestinal cancer and colorectal cancer have also been highly reported due to asbestos exposure. Asbestos is a highly hazardous chemical that was commonly used in homes and buildings starting in the 1930's.

    Asbestos was used as insulation in walls as well as the backing for flooring. What makes this chemical so harmful to people is that when dry, the small shards of asbestos break off and become airborne which then creates the chance of inhaling the chemical. If asbestos is inhaled on a consistent basis, the shards attach onto the lunch tissue and in the breathing airway. After a while of continuous exposure, shards become inflamed which can lead to the growth of cancerous tumors.

    Mesothelioma is a cancer that unfortunately is extremely difficult, if not impossible to cure. It attacks the thin lining of the lungs, abdomen and heart and typically affects 2,000-3,000 people every year. The link between Mesothelioma and asbestos was not originally known as most types of this cancer have not progressed to a cancerous form for 20-50 years after exposure. However, scientists who have researched for decades on the link have found that the two are directly related to each other.

    Lung cancer, another commonly diagnosed cancer caused by asbestos is equally as dangerous as Mesothelioma, but this cancer can be linked to other issues such as smoking or exposure to second-hand smoke and not just asbestos exposure. Some of the symptoms of lung cancer are chest pain, shortness of breath, chronic coughing, a change in color of sputum or blood in your sputum. Other symptoms include chronic fatigue, headaches and weight loss. Contact your physician immediately if you are concerned that this cancer may have been caused by a constant level of asbestos.

    Since Asbestos cancer takes such a long time to come out of dormancy, and the signs and symptoms are so subtle, that a trip to your physician is not warranted until it is too late. In cases of cancer caused by asbestos, many times these cancers are incurable because they were not aware of the sickness to begin with.

    Asbestos Laws

    Asbestos laws are laid out to protect those who have unknowingly been exposed to this harmful and hazardous chemical (at the awareness of another party). These laws were put into place to help those exposed to asbestos, who have suffered because of this exposure seek compensation.

    When you are exposed to a serious level of asbestos, you are greatly risking your chance of contracting lunch cancer, Mesothelioma or a whole other slew of long-term health issues such as breathing difficulties and problems in your peritoneum. You are also at risk of contracting a disease that is called asbestosis which is a long-time build-up of scar tissue in the lungs caused by inhaling asbestos on a regular basis. This build-up is what leads to lunch cancer or Mesothelioma. If left untreated, it can have an end result of death. This is why asbestos laws are in place.

    Many buildings built as early as 1930 contain a large level of asbestos. Many have had the asbestos removed, eliminating the risk for exposure. However, there are many dishonest business owners out there who have been made aware of the underlying issues with asbestos in their building and choose to keep quiet, possibly because of the high cost of removing the asbestos, or their lack of education in how harmful and hazardous asbestos truly is. Not making your employees aware of the dangers of asbestos exposure can land a business owner in serious hot water. Asbestos laws have been created to bring about lawsuits to companies and individuals who have been negligent on their inability to remove the asbestos from their work environment. Many people who have lost asbestos lawsuits have been forced to pay hundreds of thousands of dollars in retribution pay.

    The best thing that you can do is to follow and obey the asbestos laws. Clean up and dispose of any asbestos problems you may have in your business or home and make your employees aware that you have done so will create a healthier and a more respectable and forthright working environment. By making your employees aware that you have addressed the asbestos situation will protect you from any further risk of lawsuits brought on by different individuals.

    Mesothelioma Causes

    Wondering How You Could Have Gotten Mesothelioma Cancer?

    Several diseases are associated with exposure to asbestos. They include: malignant mesothelioma, asbestosis, pleural effusion, pleural plaques and thickening, and lung cancer.

    Prior to 1975 asbestos fibers were commonly used. You could have been exposed to asbestos while working at any number of different industries. Chief among the possibilities would be jobs at asbestos mining and milling plants, shipyards, fireproofing and heating, construction, automotive repair, insulation, pipefitting and boilermaking.

    If you did not work in one of these industries or another that used asbestos, it is also possible that you could have been exposed if someone in your household worked with asbestos and carried asbestos fibers home on his or her clothing, hair or body. You may also have been exposed indirectly by living near asbestos mines.

    Although it is true that most patients with malignant mesothelioma, lung cancer or other asbestos-related diseases likely had prolonged exposure to asbestos over a long period of time, it is also possible for one to develop one of these diseases from a brief exposure to asbestos.

    The odds of developing lung cancer from smoking also increases significantly from exposure to asbestos. Although most people with lung cancer are told that their lung cancer was caused from smoking, if you or someone you know has lung cancer and also worked in an environment that gave you exposure to asbestos, it is highly recommended that you contact an attorney that specializes in handling mesothelioma and lung cancer cases caused by exposure to asbestos. The justice system has been very generous in its rewards to people who suffer diseases caused by asbestos exposure.

    To learn more about mesothelioma cancer I recommend you visit Mesothelioma Cancer Online when searching for web resources covering mesothelioma cancer. Mesothelioma-Cancer-Online.com is an excellent resource center that offers recommendations and directory listings for numerous websites related to mesothelioma cancer, along with articles and books about mesothelioma cancer.

    Mesothelioma Symptoms

    Mesothelioma is an extremely nasty and permanent cancer that infects the membrane surrounding most internal organs. It is also a very subtle form of cancer providing only a few noticeable symptoms until it becomes extremely advanced. The most common type of mesothelioma is called pleural mesothelioma. It causes shortness of breath and/or chronic coughing that can easily be mixed up with allergies or a common cold. In many cases mesothelioma is discovered by accident when patients are looking into these symptoms. Other symptoms of pleural mesothelioma include:

    -Chest Pain

    -Chronic coughing that worsens over time

    -Shortness of breath

    -Coughing up blood

    -Fatigue

    -Wheezing

    -Lung infection

    -Swollen lymph nodes

    -Loss of appetite and weight loss

    75% of all mesothelioma cases are Pleural mesothelioma. Another type is called Peritoneal mesothelioma. Peritoneal mesothelioma affects the lining around the stomach and intestines and can be just as dangerous and deadly. Symptoms of Peritoneal mesothelioma include:

    -Pain or swelling in the abdomen

    -Weight loss

    -Bowel obstruction – blockage in the small / large intestine

    -Anemia – reduction in number of red blood cells

    -Fever

    High risk groups such as asbestos and construction workers must undergo frequent check-ups to monitor any conditions leading to mesothelioma. Because this cancer is so deadly, early diagnosis and treatment can help prolong life, but the mortality rate is usually 100% within five years.

    Current problems in the diagnosis of malignant pleural mesothelioma.

    The diagnosis of malignant pleural mesothelioma (MPM) is challenging although MPM is highly aggressive tumor. The current diagnostic gold standard is principally based on light microscopic examination of hematoxylin-eosin and immunohistochemical stains of large tissue sections. However, pathological diagnosis of MPM and classification of histological findings into 1 of the 3 subtypes (epithelial, sarcomatoid, biphasic) are difficult. We studied correlation between initial and final histological diagnosis retrospectively from the records of 21 cases with MPM from 1989 to 2005.

    The diagnosis of MPM was confirmed by histopathological examination of pleural tissue samples obtained by closed biopsy under computed tomography (CT) or ultrasonography-guided (5 cases), by biopsy under thoracoscopy with local anesthesia (9), by open biopsy via thoracotomy (2), and by video-assisted thoracoscopic surgery (VATS) [5] . Pleural biopsy under those diagnostic methods led to initial diagnosis of MPM in 15 of 21 cases (71.4%) . In 6 cases (28.6%) , initial diagnosis of MPM were not confirmed because of missing malignant tissue (1 case) and relatively small and sarcomatous element (5). In 2 cases examined by closed biopsy and in 3 examined by thoracoscopy under local anesthesia, initial diagnosis of MPM were not confirmed. To get the accurate diagnosis of MPM, obtaining large tissue samples in the initial examination by less invasive thoracoscopy is recommended

    Mesothelioma Treatment

    Once an individual has been diagnosed with mesothelioma, the next step is to discuss mesothelioma Treatment options with his/her physician. Recent scientific research has produced significant breakthroughs with regard to treatment protocols for mesothelioma patients and more options are now available for managing the disease and supporting improved quality of life. Newly diagnosed patients always have many questions about the treatment options that would be most effective for them, including questions about new treatment therapies like Alimta and Cisplatin and other chemotherapy drugs. In addition to these newer drugs that are being used to treat asbestos cancer, mesothelioma patients also have a number of "conventional" treatment options to consider, including chemotherapy, radiation therapy and surgery. Clinical trials and experimental treatments are still other options that some mesothelioma patients may be eligible to participate in.

    Our site will feature a comprehensive mesothelioma Cancer treatment section that includes important information for patients and families. We’ve included resources on top mesothelioma doctors as well as a comprehensive list of questions that you may wish to discuss with your personal physician when preparing a treatment plan. We are always providing new and informative resources regarding mesothelioma treatment including: Clinical Trials, conventional treatments, experimental therapies, and more. Check back often for the most recent advances in mesothelioma treatments.

    For your convenience, we have consolidated mesothelioma treatment information for your review. This section is updated on a weekly basis.

    Conventional Therapies

    Conventional mesothelioma therapies include surgery, radiation and chemotherapy. You should keep in mind that if you choose one course of action for mesothelioma treatment, you may preclude other courses. All of your options should be considered as soon as possible.

    Leading Doctors

    We have become familiar with medical doctors who specialize in aggressively treating malignant mesothelioma. Some of these doctors will review your medical records for free to see if you are a candidate for their mesothelioma treatment protocol.

    Cancer Centers

    Top Cancer Centers for mesothelioma treatment have been listed alphabetically by state for your convenience. Listings include contact information and Web site links where available.

    Clinical Trials

    Information about current studies of promising new or experimental mesothelioma treatments.

    Experimental Therapies

    Several forms of mesothelioma treatment such as the drug Alimta, gene therapy, immunotherapy, photodynamic therapy and multimodality therapy are still in their experimental stages.



    Thursday, March 26, 2009

    Asbestos Cancer

    Mesothelioma:
    Tumor of body cavity lining: a benign or malignant tumor of the lining of the lungs, heart, or abdomen.
    The malignant form is often the result of exposure to asbestos and may take more than 30 years to develop.

    Asbestos (Greek a-,“not”; sbestos, “extinguishable”), the fibrous form of several minerals and hydrous silicates of magnesium. The name may also be applied to the fibrous forms of calcium and iron. Asbestos fibers can be molded or woven into various fabrics. Because it is nonflammable and a poor heat conductor, asbestos has been widely used to make fireproof products such as safety clothing for fire fighters and insulation products such as hot-water piping. The first recorded use of the word asbestos is by Pliny the Elder in the 1st century ad, although the substance itself was known as early as the 2nd century bc. The Romans made cremation cloths and wicks from it, and centuries later Marco Polo noted its usefulness as cloth.

    Asbestos is of two principal classes, the amphiboles and the serpentines, the former of relatively minor importance. Chrysotile, in the serpentine class, constitutes about 95 percent of the world supply of asbestos, of which three-fourths is mined in Québec. Other large deposits exist in South Africa. In the United States, California, Vermont, and Arizona are the leading asbestos-producing states;

    however, the majority of United States deposits are of no commercial value. Asbestos is obtainable by various underground mining methods, but the most common method is open-pit mining. Only about 6 percent of the mined ore contains usable fibers. The fibers are separated from the ore by crushing, air suction, and vibrating screens, and in the process are sorted into different lengths, or grades.

    The most widely used method of grading, the Québec Standard Test Method, divides the fibers into seven groups, the longest in group one and the shortest, called milled asbestos, in group seven.

    The length of the fibers, as well as the chemical composition of the ore, determines the kind of product that can be made from the asbestos. The longer fibers have been used in fabrics, commonly with cotton or rayon, and the shorter ones for molded goods, such as pipes and gaskets.


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